Note: Hydroquinone Cream 4% is temporarily out of stock and expected to be restocked within 7 to 10 days. In the meantime, you may opt for a hydroquinone combination product if appropriate. You can also join the wishlist to receive a notification once it becomes available.
Hydroquinone Cream 4% 30g targets dark spots, melasma, post-acne marks,hyperpigmentation, sun spots, and uneven tone with dermatologist-trusted precision. This prescription product in South Africa is for night use only and must be paired with daily Sunroof sunscreen SPF 50+ to protect your skin and maintain clear, even results.
For users managing multiple pigment concerns, this product is commonly explored within a dedicated brightening & hyperpigmentation collection to support a more complete treatment routine.
Where to Buy Hydroquinone Cream 4% in South Africa
Hydroquinone Cream 4% is available to buy online in South Africa through tretinoins.co.za, with secure checkout and nationwide delivery. Each tube is factory-sealed and sourced from trusted suppliers to ensure authenticity.
Orders are shipped in discreet packaging with full tracking provided, so you can follow your delivery from dispatch to doorstep. If you’re looking to order hydroquinone cream 4% online in South Africa, this option offers reliable availability, clear usage guidance, and fast delivery support.
For experienced users who require a stronger night treatment, Tretiheal 0.1% tretinoin cream is also available as part of an advanced treatment routine when used carefully.
Key Benefits of Hydroquinone 4% Dark Spot Treatment
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Fades melasma, age spots, sun spots, and post-acne marks (PIH).
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Targets melanin at the source through tyrosinase inhibition for deeper correction.
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Promotes a visibly even tone and clearer, smoother skin appearance.
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Designed for precise spot use to reduce stubborn or patchy discoloration effectively.
Who It’s For
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Best for: Localised dark spots, melasma patches, sun damage, and post-inflammatory hyperpigmentation (PIH).
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Skin types: Normal, oily, or combination suitable for some dry skin when paired with a gentle moisturizer.
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Not for: Pregnancy or breastfeeding, broken or irritated skin, active eczema or dermatitis, or anyone with sulfite sensitivity (if the formula contains sodium metabisulfite).
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Must: Apply broad-spectrum SPF 30+ daily to protect treated areas from South Africa’s strong sun.
How to Use Hydroquinone Cream 4%
Hydroquinone Cream 4% is best used as a targeted treatment rather than a daily, long-term product. Following a proper cycle helps improve results while reducing the risk of irritation.
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Cleanse your face gently and allow skin to dry completely.
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Apply a pea-sized amount, divided into small dots, only on affected dark spots — avoid normal skin.
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Use once nightly for up to 8–12 weeks, or as directed by your skincare professional.
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Take a break: After a treatment cycle, pause use for 4 – 8 weeks before restarting if needed.
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Follow with a gentle, non-comedogenic moisturizer to maintain hydration.
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Apply SPF 30+ every morning, and reapply if you’re outdoors.
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Stop if irritation occurs: Discontinue use if you experience strong burning, redness, or peeling and seek professional advice.
Notes: Always perform a patch test (jawline, 24 hours before first use).
Avoid combining with retinoids, strong AHAs/BHAs, peels, or scrubs on the same night.
This approach supports safer use of hydroquinone 4% while helping manage stubborn pigmentation more effectively, especially when combined with products from the tretinoin all products range as part of a structured night routine.
What to Expect
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Weeks 2–4: Early signs of improvement small dark spots begin to look more balanced in tone.
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Weeks 6–8: Noticeable fading of post-acne marks and sun spots, especially with consistent SPF use.
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Weeks 8–12: Skin appears clearer, smoother, and more even-toned. Review progress with your clinician.
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Ongoing: Follow professional advice for treatment breaks or maintenance cycles to keep results stable.
Ingredients of Hydroquinone Cream 4% 30g
Active:
Hydroquinone 4% dermatology-grade brightening agent that helps fade dark spots and even skin tone.
Base:
Purified water, glycerin, cetyl and stearyl alcohols, emulsifiers, and preservatives (may vary slightly by batch).
Free From:
Added fragrance and harsh additives (if confirmed on pack).
Allergen Note:
Check the label for sodium metabisulfite, avoid if you have sulfite sensitivity.
Patch Test:
Apply a small amount on the jawline for 24 hours before full use. Stop immediately if strong irritation occurs.
Hydroquinone vs Azelaic Acid vs Tretinoin
| Feature |
Hydroquinone 4% |
Azelaic Acid (15–20%) |
Tretinoin |
| Best for |
Melasma, dark spots, PIH |
Acne, PIH, redness, uneven tone |
Acne, texture, fine lines |
| How it works |
Reduces melanin production |
Calms inflammation, reduces bacteria, improves turnover |
Speeds up skin renewal |
| Speed on dark spots |
Fast (short-term) |
Gradual & steady |
Moderate (over time) |
| Acne control |
Limited |
Good |
Strong |
| Redness / rosacea |
Not suitable |
Suitable |
May worsen |
| Sensitivity risk |
Moderate |
Low to moderate |
Moderate to high |
| Use style |
Spot treatment |
Whole face or spots |
Night use |
| Sun sensitivity |
High (SPF essential) |
Moderate (SPF needed) |
High (SPF essential) |
| Long-term use |
No (cycle only) |
Yes |
Yes (with guidance) |
| Typical role |
Target stubborn pigment |
Daily maintenance |
Core night treatment |
Choose Hydroquinone 4% if your main goal is melasma or stubborn dark spots and you plan short treatment cycles with strict sun protection. Many routines use hydroquinone for short cycles, then switch to azelaic acid cream 20% for maintenance.
Safety & Warnings
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External use only — apply on dark spots or patches, not the entire face.
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Possible effects: mild dryness, redness, or light stinging may occur; reduce frequency or pause if irritation appears.
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Do not use on broken, inflamed, or sunburned skin.
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Avoid combining on the same night with peels, strong acids, scrubs, or retinoids.
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Photosensitivity warning: wear broad-spectrum SPF daily and use hats or shade when outdoors.
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Duration: use in short, guided courses only long-term use without supervision may cause exogenous ochronosis.
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Storage: keep in a cool, dry place, away from direct sunlight. Always check batch and expiry before use.
Results & Proof of melalite forte 4%
Why It Works:
Hydroquinone Cream 4% helps reduce melanin formation by blocking tyrosinase activity, the enzyme responsible for pigmentation. With consistent night use and strict daily SPF, it visibly evens skin tone and lightens dark spots over time.
Pack Info & What’s Included
One 30g Tube designed for targeted spot use, lasting several weeks with proper application.
Instruction Leaflet includes:
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Safe ramp-up schedule and usage duration
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Guidance on treatment cycles and when to pause
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SPF protection rules and aftercare tips
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Customer support contacts for pharmacist or skincare assistance
Pair With
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Gentle Cleanser (No Acids) keeps skin clean without stripping or irritation.
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Niacinamide or Ceramide Moisturizer supports the barrier and reduces dryness during treatment.
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Broad-Spectrum SPF 30+ (Daily, SA Sun) essential to protect treated skin from re-darkening.
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Optional Day Brighteners use vitamin C or azelaic acid on alternate mornings (never on the same night as hydroquinone).
Delivery & Returns South Africa
Delivery:
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Major metros: 1 – 3 working days
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Outlying areas: 3 – 5 working days
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Discreet packaging with full tracking provided
Returns:
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Accepted within 7 days for sealed and unused products
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Refund processed within 3 – 5 working days after inspection
FAQs Hydroquinone 4% in South Africa
How long until I see changes?
Most users notice a lighter, more even tone in 6–8 weeks with consistent use and daily SPF protection.
Can I use it with vitamin C, niacinamide, or azelaic acid?
Yes, but alternate use only. Apply Hydroquinone at night and brighteners in the morning. Don’t layer them together.
Is hydroquinone 4% good for melasma and PIH?
Yes. Hydroquinone cream 4% is commonly used for melasma and post-inflammatory hyperpigmentation (PIH), particularly when darker patches do not respond to gentler treatments.
What if I forget a dose?
Skip that night and apply the next evening. Avoid doubling the amount.
Can hydroquinone cream 4% remove dark spots fast?
Hydroquinone works faster than many other brightening treatments, but results vary. Visible fading may begin within a few weeks when used correctly with daily sun protection.
Where can I buy hydroquinone cream 4% in South Africa?
You can buy hydroquinone cream 4% online in South Africa through trusted local stores that offer sealed products, discreet packaging, and tracked delivery.
Can I use it on the whole face?
No, Hydroquinone 4% is a spot treatment for local areas only, not full-face application.
Can I use hydroquinone 4% with tretinoin?
Yes, some routines use hydroquinone and tretinoin on alternate nights. This should be done carefully to reduce irritation.
What is the price of hydroquinone cream 4% in South Africa?
The hydroquinone 4% cream price in South Africa can vary based on brand and availability. Always check the product page for the latest pricing.
How long can I use Hydroquinone 4%? Do I need treatment breaks?
Typically used for 8–12 weeks per cycle. Take breaks between courses as advised by your healthcare professional to avoid side effects.
What helps if I get dry patches or irritation?
Use a ceramide or niacinamide moisturizer twice daily and reduce frequency. If irritation persists, pause and consult your pharmacist.
Can skin brightening creams remove dark spots?
Some skin brightening creams can help fade dark spots over time, especially when paired with sunscreen and consistent use.
Which hyperpigmentation cream should I buy?
The right choice depends on your concern. Hydroquinone is often chosen for stubborn dark spots, while other treatments suit milder pigmentation.