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South Africa’s #1 Trusted Tretinoin Source
All Skincare & Tretinoin Products in South Africa
Explore our full range of authentic skincare: tretinoin creams and gels, dark spot and melasma treatments, acne gels, SPF 50 sunscreens and minoxidil hair care. Find the right product and strength for your skin, delivered across South Africa.
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Add to CartTretinoins Cream Store Acnetop Gel 20g by Healing Pharma for Pimples and Inflamed AcneRegular price R 250.00R 300.00Sale priceAdd to Cart
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Shop Authentic Skincare and Tretinoin Products in South Africa
Welcome to the full range at tretinoins.co.za. Every product we stock is chosen for a clear skin concern: acne and clogged pores, dark spots and melasma, fine lines and texture, daily sun protection and thinning hair. You will find trusted pharmaceutical brands such as Tretiheal, A-Ret, Tretin, Glenmark and UV Doux, in the strengths and formats South African customers ask for most.
Not sure where to start? Use the categories and skin concerns below to narrow down your options, or read our Tretinoin Buying Guide to choose the right strength for your skin.
Shop by Category
Tretinoin Creams
Our tretinoin creams come in 0.025%, 0.05% and 0.1% strengths from Tretiheal and Tretin. The cream base feels richer, which suits normal to dry skin and anyone starting a retinoid routine. Most first-time users begin with Tretiheal Tretinoin Cream 0.025%.
Tretinoin Gels
A-Ret tretinoin gels are lightweight and oil free, so they work well for oily, combination and acne-prone skin, especially in hot weather. For a stronger retinoid option for clogged pores and texture, see Tazret Forte Tazarotene Cream 0.1%.
Skin Brightening and Hyperpigmentation
Target dark spots, acne marks and melasma with our skin brightening and hyperpigmentation range, including Hydroquinone Cream 4%, Azelaic Acid Cream 20%, Melaglow and Triluma.
Anti-Acne and Anti-Wrinkle Treatments
Our anti-acne and anti-wrinkle treatments bring together retinoids, Acnetop Gel for red, inflamed pimples, Sebogel for oily skin and blackheads, and gentle cleansing options.
Sunscreens
Daily SPF protects your skin and your results. Browse our SPF 50 sunscreens: a matte gel for oily skin, a tinted mineral sunscreen for sensitive and pigmentation-prone skin, and an everyday lotion for face and body.
Minoxidil and Hair Loss Care
For thinning hair, explore our minoxidil hair loss treatments, including Minoxidil 5% topical solution, a minoxidil and finasteride combination, and a 0.5mm derma roller for scalp care.
Shop by Skin Concern
- Acne and breakouts: tretinoin gel or cream for clogged pores, Acnetop for inflamed pimples, Sebogel for excess oil.
- Dark spots, acne marks and melasma: hydroquinone, azelaic acid or tretinoin, always paired with daily SPF 50.
- Fine lines and rough texture: tretinoin 0.025% to start, building to 0.05% or 0.1% as your skin adjusts.
- Oily skin in summer: an oil-free gel retinoid and a matte sunscreen.
- Sensitive skin: start with the lowest strength, use it every second or third night, and choose a mineral sunscreen.
- Thinning hair: minoxidil applied consistently, with a derma roller as optional support.
A Simple Starter Routine
- Morning: gentle cleanser, moisturiser, then a broad-spectrum SPF 50 sunscreen.
- Evening: cleanse, wait until skin is completely dry, apply a pea-sized amount of your retinoid or brightening treatment, then moisturise.
- Start slowly: use a new retinoid two to three nights a week and increase as your skin settles. Mild dryness and peeling in the first weeks are common.
Why Shop with Tretinoins.co.za
- Authentic products from established pharmaceutical brands.
- Fast dispatch: most orders leave within 24 hours on working days.
- Delivery options across South Africa: The Courier Guy, SkyPoint and PEP Store collection. See our shipping policy for costs and times.
- Free shipping on orders over R1500.
- Discreet packaging on every order.
- Pay later with Payflex at checkout.
- WhatsApp support on +27 68 067 4421 for product questions.
Want to learn more first? Read About Tretinoin or browse our skincare blog for routines, comparisons and ingredient guides.
Frequently Asked Questions
Are your products authentic?
Yes. We stock original products from established pharmaceutical manufacturers such as Healing Pharma, Menarini, H&H, Glenmark and Brinton, and each product page shows the brand, strength and pack size.
Which tretinoin strength should I start with?
Most people start with 0.025% and move to 0.05% or 0.1% once their skin adjusts. Our Tretinoin Buying Guide explains how to choose based on your skin type and concern.
Should I choose a tretinoin cream or a gel?
Creams suit normal to dry skin and beginners because they feel more moisturising. Gels are lighter and oil free, so they suit oily and acne-prone skin and hot weather.
Which products help with dark spots and melasma?
Hydroquinone 4%, azelaic acid 20% and tretinoin are the most common options for dark spots, acne marks and melasma. Whichever you choose, daily SPF 50 is essential, because sun exposure brings pigmentation back.
Do I need sunscreen when using tretinoin or hydroquinone?
Yes. Retinoids and brightening treatments make your skin more sensitive to the sun. Apply a broad-spectrum SPF 50 every morning and reapply every 2 to 3 hours when you are outdoors.
Can I use retinoids during pregnancy?
No. Tretinoin and tazarotene should not be used if you are pregnant, trying to fall pregnant or breastfeeding. Speak to a healthcare professional about safer alternatives.
How long does delivery take in South Africa?
Most orders are dispatched within 24 hours on working days. Delivery then takes about 3 to 10 working days depending on the option you choose at checkout, from PEP Store Express and The Courier Guy to PEP Store Saver. Full details are on our shipping policy page.
Do you offer free shipping or pay later options?
Yes. Shipping is free on orders over R1500, and you can split your payment with Payflex at checkout.
What is your returns policy?
You can request a return within 7 calendar days of delivery or collection for items that are unused, unopened, sealed and in their original packaging. Email contact@tretinoins.co.za to start a return. Approved refunds are processed within 7 calendar days after we receive and inspect the item. Full details are on our return and refund policy page.
